HPLC and CE: Principles and Practice presents the latest information on the most powerful separation techniques available: high-performance liquid chromatography (HPLC) and capillary electrophoresis (CE). Fundamental theory, instrumentation, modes of operation, and optimization of separations are presented in a concise, nontechnical style to help the user choose the appropriate technique quickly and accurately. Well-illustrated and containing convenient end-of-chapter summaries of the major concepts, the book provides in-depth coverage of troubleshooting, improvement of resolution, data manipulation, selectivity, and sensitivity.Graduate students, technicians, and researchers who must use separations yet have little or no background in analytical chemistry can overcome "separation anxiety" and begin obtaining the best possible separations in minimal time. The book will also be useful to analytical chemists who would like a better understanding of HPLC and CE theory and processes.