This volume presents the new objectives of physics on self-organizing systems composed of multi-components, in order to create a new field and establish universal comprehension in physics. The book covers broad topics such as the thermodynamic time asymmetry in both transient and stationary nonequilibrium states, the seriousness of auxiliary conditions in physicochemical processes and biological systems, the quantum-classical and micro-macro interfaces which are familiar in mesoscopic physics, the purification scheme of quantum entanglement, topics on gamma-ray bursts, and the walking mechanism of single molecular motors.