This book constitutes the refereed proceedings of the Second International Conference on Natural Language Processing, NLP 2000, held in Patras, Greece, in June 2000. The 39 revised full papers presented were carefully reviewed and selected from a total of 71 submissions. The book is organized in topical sections on tokenization and morphological analysis, lexical knowledge representation, parsing and discourse analysis, anaphora resolution, machine translation, language generation, man-machine interaction and word sense recognition/disambiguation, and information extraction.