Hand Transplantation has been the dream of humanity until 1998, when a group of international surgeons gathered in Lyon performed the first of many hand transplantations carried out since then. This book presents the global international experimental and clinical experience on limb transplantation and other composite tissue allografts. It represents the most complete and comprehensive review of all aspects of this innovative and ground breaking procedure. They range from the experimental basis of hand transplantation, to surgical techniques, to immunology and antirejection drug strategies, to selection of the ideal candidates and preparation of a successful hand transplantation program, to the dermatological, psychological and medico-legal implications of this new procedure, to the rehabilitation of the transplanted hand including brain remodelling and sensibility recovery, to the presentation of the current functional results and future directions, including the possibility to introduce face and uterus transplantation to the clinical practice. A section of selected videos outlines the function of the transplanted hand in the daily living activities and the professional life of these patients. This book represent a milestone in the medical .literature and is a great asset for every scientific library.