This is a comprehensive volume on the theories and applications of evidence-based anesthesia and critical care. Arising from the internationally renowned Cochrane Collaboration - the global force in evidence-based medicine - this book will be an authoritative guide for anesthetists. As coordinators of the Cochrane Anaesthesia Review Group, the editors have gathered a formidable set of contributions from around the world. The first half of the book provides an introduction to evidence-based medicine and applies the principles to anesthesia and critical care, including critical appraisal, meta-analysis, interpreting results and controlling bias. The second half shows how to practice this in preoperative evaluation, regional and general anesthesia, postoperative pain therapy, critical care and acute medicine. Medical professionals working in anesthesia and surrounding specialties worldwide will find this book immensely useful.